RESUMO
The wild species of the genus Zea commonly named teosintes, comprise nine different taxa, distributed from northern Mexico to Costa Rica. Although this genus of plants has been extensively studied from a morphological, ecogeographical and genetic point of view, most contributions have been limited to the study of a few populations and taxa. To understand the great variability that exists between and within teosinte species, it is necessary to include the vast majority of known populations. In this context, the objective of this work was to evaluate the diversity and genomic structure of 276 teosinte populations. Molecular analyzes were performed with 3,604 plants and with data from 33,929 SNPs. The levels of genetic diversity by taxonomic group show a marked difference between species, races and sections, where the highest values of genomic diversity was found in ssp. parviglumis and ssp. mexicana. The lower values were obtained for the Luxuriantes section as well as ssp. huehuetenagensis of the section Zea. The results of structure show that there is a great genetic differentiation in all the taxonomic groups considered. For ssp. parviglumis and mexicana, which are the taxa with the largest number of populations, a marked genomic differentiation was found that is consistent with their geographic distribution patterns. These results showed a loss of diversity in several teosinte populations, making a strong case for further collection, and ex situ and in situ conservation. Also, this study highlights the importance of integrating genomic diversity and structure for the applications of conservation and management.
Assuntos
Genoma , Zea mays , Zea mays/genética , Genômica , Polimorfismo de Nucleotídeo Único , Deriva GenéticaRESUMO
La hipertensión arterial secundaria es más común en individuos menores de 30 años, la mayor parte son de causa renovascular; la etiología endocrina es excepcional, el hiperaldosteronismo primariosólo ocupa de 5-15%, el síndrome de Conn corresponde a 0.05-2.2% de la población de hipertensos y es una de las pocas causas potencialmente curables de hipertensión, por lo que consideramos este caso digno de ser revisado. Se presenta un hombre de 63 años de edad con hipertensión arterialdiagnosticada hace 25 años, en tratamiento con múltiples antihipertensivos, incluido el minoxidil sin control de cifras tensionales, que consulta a endocrinología por aparición de vello facial. Se consideró hipertensión arterial secundaria y se halló hipokalemia. La relación de aldosterona y renina elevada, sugería la presencia de hiperaldosteronismo, que se localizó con venografía de suprarrenales. La extirpación quirúrgica de la lesión confirmó el diagnóstico de adenoma adrenocortical. Después de la cirugía mejoró el control de la tensión arterial y tras suspender el minoxidil, la hipertricosis desaparece. (Acta Med Colomb 2014; 39: 191-195).
Secondary Hypertension is more common in individuals under 30; most have renovascular etiology; endocrine etiology is exceptional; primary hyperaldosteronism is only responsible for 5-15%, Conn syndrome corresponds to 0.05-2.2 % of the hypertensive population and is one of the few potentially curable causes of hypertension, so we consider this case worthy to be revised. A 63 year old man diagnosed with hypertension 25 years ago and treated with multiple antihypertensives including minoxidil, with uncontrolled blood pressure readings, which consults to endocrinology for appearance of facial hair, is presented. Secondary hypertension was considered, and hypokalemia was found. The ratio of aldosterone and high renin, suggested the presence of hyperaldosteronism which was localized by adrenal venography. Surgical removal of the lesion confirmed the diagnosis of adrenocortical adenoma. After surgery, control of blood pressure improved and after discontinuation of minoxidil, hypertrichosis disappears. (Acta Med Colomb 2014; 39: 191-195).
Assuntos
Humanos , Masculino , Pessoa de Meia-Idade , Adenoma Adrenocortical , Pressão Sanguínea , Renina , Aldosterona , Hiperaldosteronismo , HipertensãoRESUMO
Se exponen los elementos básicos de Libros para la vida, un proyecto para la promoción de la lectura en la sala de pediatría del Instituto Nacional de Oncología y Radiobiología de Cuba. Se tratan los fundamentos de las actividades de promoción de la lectura, sus aspectos metodológicos y sus herramientas. Se detallan las experiencias adquiridas por los autores durante la ejecución de las diferentes etapas del proyecto
Assuntos
Humanos , Masculino , Feminino , Criança , Qualidade de Vida , Leitura , Livros , Cuba , Saúde da Criança , Criança Hospitalizada/educação , Serviço Hospitalar de OncologiaRESUMO
Se exponen los elementos básicos de "Libros para la vida", un proyecto para la promoción de la lectura en la sala de pediatría del Instituto Nacional de Oncología y Radiobiología de Cuba. Se tratan los fundamentos de las actividades de promoción de la lectura, sus aspectos metodológicos y sus herramientas. Se detallan las experiencias adquiridas por los autores durante la ejecución de las diferentes etapas del proyecto(AU)
